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Thursday, June 22, 2017

BHA and BHT in cosmetics

Butylated compounds, includes BHA and BHT are commonly found in cosmetics.

Butylated compounds are found in creams, lip products, makeup, hair products, sunscreen, fragrance, antiperspirant/deodorant, and more. Some studies have shown they can influence hormones in the body, can be toxic to some organs, can cause with child development, and may cause cancer. The compounds have many names, but here's one: butylated hydroxyanisole. It has a CAS No. 25013-16-5.

From the NTP report on Butylated Hydroxyanisole:
Dietary exposure to BHA caused benign and malignant tumors of the forestomach (papilloma and squamous-cell carcinoma) in rats of both sexes and in male mice and hamsters (IARC 1986, Masui et al. 1986). Since BHA was listed in the Sixth Annual Report on Carcinogens, an additional study in experimental animals has been identified. Dietary administration of BHA to fish (hermaphroditic Rivulus marmoratus) as larvae caused liver cancer (hepatocellular carcinoma) in the adult fish (Park et al. 1990).

Currently there is not enough data to say whether BHA causes cancer in humans, but gathering more data on this can  take years.

The best action to take is to avoid butylated compounds, and help your kids do the same. Check all lotions, chapstick, lip gloss, and anything they put on their skin.
 

Sources
  1. SafeCosmetics.org
  2. National Toxicology Program, “Report on Carcinogens, Twelfth Edition. Butylated Hydroxyanisole,” 2011. https://ntp.niehs.nih.gov/ntp/roc/content/profiles/butylatedhydroxyanisole.pdf. [Last accessed 6/12/2017].
  3. Environmental Working Group, “Skin Deep. Butylated Hydroxytoluene,” [Online]. Available: http://www.ewg.org/skindeep/ingredient/700741/BHT/. [Accessed 20 June 2013].
  4. Environmental Working Group, “Skin Deep. Butylated Hydroxyanisole,” [Online]. Available: http://www.ewg.org/skindeep/ingredient/700740/BHA/. [Accessed 20 June 2013].
  5. Labrador V et al., “Cytotoxicity of butylated hydroxyanisole in Vero cells,” Cell biology and toxicology, vol. 23, no. 3, pp. 189-99, 2007.
  6. Lanigan RS, Yamarik TA, “Final report on the safety of assessment of BHT (1),” International journal of toxicology, vol. 21, no. Suppl 2, pp. 19-94, 2002.
  7. Jeong SH et al, “Effects of butylated hydroxyanisole on the development and functions of reproductive system in rats,” Toxicology, vol. 208, no. 1, pp. 49-62, 2005.
  8. Masui T et al, “Sequential changes of the forestomach of F344 rats, Syrian golden hamsters, and B6C3F1 mice treated with butylated hydroxyanisole,” Japanese journal of cancer research, vol. 77, no. 11, pp. 1083-90, 1986.
  9. Botterweck AA, “Intake of butylated hydroxyanisole and butylated hydroxytoluene and stomach cancer risk: results from analyses in the Netherlands Cohort Study,” Food and chemical toxicology, vol. 38, no. 7, pp. 599-605, 2000.

[1] National Toxicology Program, “Report on Carcinogens, Twelfth Edition. Butylated Hydroxyanisole,” 2011.
[2] Environmental Working Group, “Skin Deep. Butylated Hydroxytoluene,” [Online]. Available: http://www.ewg.org/skindeep/ingredient/700741/BHT/. [Accessed 20 June 2013].
[3] Environmental Working Group, “Skin Deep. Butylated Hydroxyanisole,” [Online]. Available: http://www.ewg.org/skindeep/ingredient/700740/BHA/. [Accessed 20 June 2013].
[4] Labrador V et al., “Cytotoxicity of butylated hydroxyanisole in Vero cells,” Cell biology and toxicology, vol. 23, no. 3, pp. 189-99, 2007.
[5] Lanigan RS, Yamarik TA, “Final report on the safety of assessment of BHT (1),” International journal of toxicology, vol. 21, no. Suppl 2, pp. 19-94, 2002.
[6] Jeong SH et al, “Effects of butylated hydroxyanisole on the development and functions of reproductive system in rats,” Toxicology, vol. 208, no. 1, pp. 49-62, 2005.
[7] Masui T et al, “Sequential changes of the forestomach of F344 rats, Syrian golden hamsters, and B6C3F1 mice treated with butylated hydroxyanisole,” Japanese journal of cancer research, vol. 77, no. 11, pp. 1083-90, 1986.
[8] Botterweck AA, “Intake of butylated hydroxyanisole and butylated hydroxytoluene and stomach cancer risk: results from analyses in the Netherlands Cohort Study,” Food and chemical toxicology, vol. 38, no. 7, pp. 599-605, 2000. - See more at: http://www.safecosmetics.org/get-the-facts/chemicals-of-concern/butylated-compounds/#sthash.mC56wdYz.dpuf

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